Name: Human V1AR-Strep full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP120490

Tag	C-Flag&Strep Tag
Target	V1AR
Synonyms	AVPR V1a, AVPR1, V1aR
Description	Human V1AR-Strep full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	P37288
Expression Host	HEK293
Protein Families	GPCR,Transmembrane,Druggable Genome,
Protein Pathways	GPCRDB Class A Rhodopsin-like,Peptide GPCRs,
Molecular Weight	The human full length V1AR-Strep protein has a MW of 46.8 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with pH lower than 6.5 in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis. [provided by RefSeq, Jul 2008]
Usage	Research use only
Conjugate	Unconjugated

Human V1AR-Strep full length protein-synthetic nanodisc