Name: Human PTH1R-Strep full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP120451

Tag	C-Flag&Strep Tag
Target	PTH1R
Synonyms	EKNS, PFE, PTHR, PTHR1
Description	Human PTH1R-Strep full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	Q03431
Expression Host	HEK293
Protein Families	GPCR,Transmembrane,Druggable Genome,
Protein Pathways	Endochondral Ossification,GPCRDB Class B Secretin-like,Osteoblasts,Cancer,
Molecular Weight	The human full length PTH1R-Strep protein has a MW of 66.4 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with pH lower than 6.5 in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010]
Usage	Research use only
Conjugate	Unconjugated

Human PTH1R-Strep full length protein-synthetic nanodisc

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Human PTH1R-Strep full length protein-synthetic nanodisc

Product Data

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