Name: Human NTR2-Strep full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP120373

Tag	C-Flag&Strep Tag
Target	NTR2
Synonyms	NTR2
Description	Human NTR2-Strep full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	O95665
Expression Host	HEK293
Protein Families	GPCR,Transmembrane,Druggable Genome,
Protein Pathways	GPCRDB Class A Rhodopsin-like,Peptide GPCRs,
Molecular Weight	The human full length NTR2-Strep protein has a MW of 45.4 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with pH lower than 6.5 in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	The protein encoded by this gene belongs to the G protein-coupled receptor family that activate a phosphatidylinositol-calcium second messenger system. Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands already described for neurotensin NT1 receptor. However, unlike NT1 receptor, this gene recognizes, with high affinity, levocabastine, a histamine H1 receptor antagonist previously shown to compete with neurotensin for low-affinity binding sites in brain. These activities suggest that this receptor may be of physiological importance and that a natural agonist for the receptor may exist. [provided by RefSeq, Jul 2008]
Usage	Research use only
Conjugate	Unconjugated

Human NTR2-Strep full length protein-synthetic nanodisc

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Human NTR2-Strep full length protein-synthetic nanodisc

Product Data

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