Name: Human GPBAR1-Strep full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP120287

Tag	C-Flag&Strep Tag
Target	GPBAR1
Synonyms	BG37, GPCR19, GPR131, M-BAR, TGR5
Description	Human GPBAR1-Strep full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	Q8TDU6
Expression Host	HEK293
Protein Families	Druggable Genome,
Protein Pathways	N/A
Molecular Weight	The human full length GPBAR-Strep protein has a MW of 35.2 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
Usage	Research use only
Conjugate	Unconjugated

Human GPBAR1-Strep full length protein-synthetic nanodisc