Name: Human GABR2-Strep full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP120252

Tag	C-Flag&Strep Tag
Target	GABR2
Synonyms	DEE59, EIEE59, GABABR2, GPR51, GPRC3B, HG20, HRIHFB2099, NDPLHS
Description	Human GABR2-Strep full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	O75899
Expression Host	HEK293
Protein Families	GPCR,Transmembrane,Druggable Genome,
Protein Pathways	GPCRDB Class C Metabotropic glutamate pheromone,
Molecular Weight	The human full length GABR2-Strep protein has a MW of 105.8 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with pH lower than 6.5 in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010]
Usage	Research use only
Conjugate	Unconjugated

Human GABR2-Strep full length protein-synthetic nanodisc

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Human GABR2-Strep full length protein-synthetic nanodisc

Product Data

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