Name: Human DRD3-Strep full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP120231

Tag	C-Flag&Strep Tag
Target	DRD3
Synonyms	D3DR, ETM1, FET1
Description	Human DRD3-Strep full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	P35462
Expression Host	HEK293
Protein Families	GPCR,Transmembrane,Druggable Genome,
Protein Pathways	GPCRDB Class A Rhodopsin-like,GPCRDB Other,Monoamine GPCRs,
Molecular Weight	The human full length DRD3-Strep protein has a MW of 44.2 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with pH lower than 6.5 in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD). [provided by RefSeq, Jul 2008]
Usage	Research use only
Conjugate	Unconjugated

Human DRD3-Strep full length protein-synthetic nanodisc

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Human DRD3-Strep full length protein-synthetic nanodisc

Product Data

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