Name: Human CRFR2-Strep full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP120227

Tag	C-Flag&Strep Tag
Target	CRFR2
Synonyms	CRF-RB, CRF2, CRFR2, HM-CRF
Description	Human CRFR2-Strep full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	Q13324
Expression Host	HEK293
Protein Families	Transmembrane,Druggable Genome,
Protein Pathways	GPCRDB Class B Secretin-like,Apoptosis,Neurotrophin & Receptors,
Molecular Weight	The human full length CRFR2-Strep protein has a MW of 47.7 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with pH lower than 6.5 in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	The protein encoded by this gene belongs to the G-protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH-related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. Studies in mice suggest that this receptor maybe involved in mediating cardiovascular homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jan 2011]
Usage	Research use only
Conjugate	Unconjugated

Human CRFR2-Strep full length protein-synthetic nanodisc

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Human CRFR2-Strep full length protein-synthetic nanodisc

Product Data

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