Name: Human ACM4-Strep full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP120180

Tag	C-Flag&Strep Tag
Target	ACM4
Synonyms	HM4, M4R
Description	Human ACM4-Strep full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	P08173
Expression Host	HEK293
Protein Families	Druggable Genome,
Protein Pathways	Calcium regulation in cardiac cells,GPCRDB Class A Rhodopsin-like,Monoamine GPCRs,Regulation of Actin Cytoskeleton KEGG,
Molecular Weight	The human full length ACM4-Strep protein has a MW of 53 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, mouse studies link its function to adenylyl cyclase inhibition. [provided by RefSeq, Jul 2008]
Usage	Research use only
Conjugate	Unconjugated

Human ACM4-Strep full length protein-synthetic nanodisc

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Human ACM4-Strep full length protein-synthetic nanodisc

Product Data

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