Name: Human XCR1 full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP100120
Price: 8000.00 CNY
Availability: InStock

Tag	C-Flag Tag
Target	XCR1
Synonyms	CCXCR1; GPR5
Description	Human XCR1 full length protein-synthetic nanodisc
Delivery	In Stock
Uniprot ID	P46094
Expression Host	HEK293
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	Chemokine signaling pathway, Cytokine-cytokine receptor interaction
Molecular Weight	The human full length XCR1 protein has a MW of 38.5 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	The protein is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Several alternatively spliced transcript variants encoding the same protein have been found for this gene.
Usage	Research use only
Conjugate	Unconjugated

Human XCR1 full length protein-synthetic nanodisc