Human TIGIT Protein, mFc Tag

Name: Human TIGIT Protein, mFc Tag - 专注肿瘤免疫
SKU: PME100505
Price: 3999.00 CNY
Availability: InStock

Price: 10μg ￥727.00 ; 50μg ￥2666.00 ; 100 μg ￥3999.00

SKU: PME100505 Category: ECD Proteins

Datasheet

MSDS

Product Data

Target	TIGIT
Synonyms	TIGIT;VSIG9;VSTM3
Description	Recombinant human TIGIT Protein with C-terminal mouse Fc tag
Delivery	In Stock
Uniprot ID	Q495A1
Expression Host	HEK293
Tag	C-Mouse Fc Tag
Molecular Characterization	TIGIT(Met22-Pro141) mFc(Pro99-Lys330)
Molecular Weight	The protein has a predicted molecular mass of 39.24 kDa after removal of the signal peptide.The apparent molecular mass of TIGIT-mFc is approximately 40-53 kDa due to glycosylation.
Purity	The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution	Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity, this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.
Usage	Research use only
Conjugate	Unconjugated

图片

Figure 1. Human TIGIT Protein, mFc Tag on SDS-PAGE under reducing condition.

Figure 2. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human TIGIT, mFc tagged protein (PME100505) can bind Anti-TIGIT Neutralizing antibody BME100024 in a linear range of 0.13-16.0 ng/ml.

Human TIGIT Protein, mFc Tag

Product Data

图片

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