Human STEAP1-Strep full length protein-synthetic nanodisc

Price: 10 μg ￥5670.00 ;50 μg ￥27000.00 ; 100 μg ￥49500.00

SKU: FLP120070 Category: Full Length Transmembrane Proteins

Tag	C-Flag&Strep Tag
Target	STEAP1
Synonyms	PRSS24; STEAP
Description	Human STEAP1-Strep full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	Q9UHE8
Expression Host	HEK293
Protein Families	Transmembrane
Protein Pathways	N/A
Molecular Weight	The human full length STEAP1-Strep protein has a MW of 39.9 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	STEAP1 is a cell-surface biomolecule composed by sixtransmembrane domains connected by intra- and extracellular loops. It is commonly found overexpressed in several types of cancers, namely in PCa, and is preferentially located at the tight or gap junctions. However, in nontumoural tissues and vital organs, STEAP1 protein presents low or absent expression, unveiling considerable specificity for cancer environment. Taking into account STEAP1 predicted transmembrane topology and cellular localization, it has been hypothesized that STEAP1 may play an important role as a transporter protein and can be involved in intercellular communication.
Usage	Research use only
Conjugate	Unconjugated