Human PLA2R1 full length protein-synthetic nanodisc

Name: Human PLA2R1 full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP100147
Price: 8000.00 CNY
Availability: InStock

Price: 10 μg ￥6300.00 ;50 μg ￥30000.00 ; 100 μg ￥55000.00

SKU: FLP100147 Category: Full Length Transmembrane Proteins Tag: synthetic nanodisc

Datasheet

MSDS

Product Data

Tag	C-Flag Tag
Target	PLA2R1
Synonyms	CLEC13C; PLA2-R; PLA2G1R; PLA2IR; PLA2R
Description	Human PLA2R1 full length protein-synthetic nanodisc
Delivery	In Stock
Uniprot ID	Q13018
Expression Host	HEK293
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	N/A
Molecular Weight	The human full length PLA2R1 protein has a MW of 168.6 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	This protein is a phospholipase A2 receptor. The protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified.
Usage	Research use only
Conjugate	Unconjugated

图片

elisa-FLP100147 PLA2R1 Fig.1 Elisa 1
Figure1. Elisa plates were pre-coated with Flag Tag PLA2R1-Nanodisc (0.2μg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with PLA2R1-Nanodisc is 3.595ng/ml.
page-FLP100147 PLA2R1 Fig.2 SDS PAGE 1
Figure2. Human PLA2R1-Nanodisc, Flag Tag on SDS-PAGE

Human PLA2R1 full length protein-synthetic nanodisc

Product Data

图片

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