Name: Human PAR3-Strep full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP120442

Tag	C-Flag&Strep Tag
Target	PAR3
Synonyms	PAR-3, PAR3
Description	Human PAR3-Strep full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	O00254
Expression Host	HEK293
Protein Families	GPCR,Transmembrane,Druggable Genome,
Protein Pathways	GPCRDB Class A Rhodopsin-like,
Molecular Weight	The human full length PAR3-Strep protein has a MW of 42.5 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	This gene encodes a member of the protease-activated receptor (PAR) family which is a subfamily of the seven transmembrane G protein-coupled cell surface receptor family. The encoded protein acts as a cofactor in the thrombin-mediated cleavage and activation of the protease-activated receptor family member PAR4. The encoded protein plays an essential role in hemostasis and thrombosis. Alternate splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Feb 2012]
Usage	Research use only
Conjugate	Unconjugated

Human PAR3-Strep full length protein-synthetic nanodisc