Name: Human PAR1 full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP100441

Tag	C-Flag Tag
Target	PAR1
Synonyms	CF2R, HTR, PAR-1, PAR1, TR
Description	Human PAR1 full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	P25116
Expression Host	HEK293
Protein Families	GPCR,Transmembrane,Druggable Genome,
Protein Pathways	GPCRDB Class A Rhodopsin-like,GPCRDB Other,Regulation of Actin Cytoskeleton KEGG,Apoptosis,Cancer,Cell Cycle,
Molecular Weight	The human full length PAR1 protein has a MW of 47.4kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with pH lower than 6.5 in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	Coagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
Usage	Research use only
Conjugate	Unconjugated

Human PAR1 full length protein-synthetic nanodisc