Name: Human HRH3-Strep full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP120133

Tag	C-Flag&Strep Tag
Target	HRH3
Synonyms	GPCR97; HH3R
Description	Human HRH3-Strep full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	Q9Y5N1
Expression Host	HEK293
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Neuroactive ligand-receptor interaction
Molecular Weight	The human full length HRH3-Strep protein has a MW of 48.7 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system.
Usage	Research use only
Conjugate	Unconjugated

Human HRH3-Strep full length protein-synthetic nanodisc