Name: Human HCAR3 full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP100329

Tag	C-Flag Tag
Target	HCAR3
Synonyms	GPR109B, HCA3, HM74, PUMAG, Puma-g
Description	Human HCAR3 full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	P49019
Expression Host	HEK293
Protein Families	GPCR,Transmembrane,Druggable Genome,
Protein Pathways	Chemokines,Chemokine and Receptor,G-Protein Coupled Receptors Signaling Pathway,
Molecular Weight	The human full length HCAR3 protein has a MW of 44.5kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with pH lower than 6.5 in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	Receptor for 3-OH-octanoid acid mediates a negative feedback regulation of adipocyte lipolysis to counteract prolipolytic influences under conditions of physiological or pathological increases in beta-oxidation rates. Acts as a low affinity receptor for nicotinic acid. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet.[UniProtKB/Swiss-Prot Function]
Usage	Research use only
Conjugate	Unconjugated

Human HCAR3 full length protein-synthetic nanodisc