Target | |
---|---|
Synonyms | DIAR6;GC-C;GUC2C;MECIL;MUCIL;STAR |
Description | Recombinant human GUCY2C protein with C-terminal 6×His tag |
Delivery | In Stock |
Uniprot ID | P25092 |
Expression Host | HEK293 |
Tag | C-6×His Tag |
Molecular Characterization | GUCY2C(Ser24-Gln430) 6×His tag |
Molecular Weight | The protein has a predicted molecular mass of 46.8 kDa after removal of the signal peptide. The apparent molecular mass of GUCY2C-His is approximately 55-130 kDa due to glycosylation. |
Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | This gene encodes a transmembrane protein that functions as a receptor for endogenous peptides guanylin and uroguanylin, and the heat-stable E. coli enterotoxin. The encoded protein activates the cystic fibrosis transmembrane conductance regulator. Mutations in this gene are associated with familial diarrhea (autosomal dominant) and meconium ileus (autosomal recessive). [provided by RefSeq, Nov 2016] |
Usage | Research use only |
Conjugate | Unconjugated |
Human GUCY2C Protein, His Tag
Price: 10μg ¥782.00 ; 50μg ¥2866.00 ; 100 μg ¥4299.00
Product Data
图片
Figure 1. Human GUCY2C Protein, His Tag on SDS-PAGE under reducing condition.
Figure 2. ELISA plate pre-coated by 1 μg/mL (100 μL/well) Human GUCY2C protein, His Tag (PME100262) can bind Anti-GUCY2C Neutralizing antibody (BME100067) in a linear range of 3.2-400 ng/mL.
Figure 3. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human GUCY2C Protein, His Tag (PME100262) can bind Anti-GUCY2C(ICTCAR-CRC) mAb (BME100180) in a linear range of 1.60–40 ng/mL.
相关产品
Monoclonal Antibodies
SKU: DMC100387 Target: GUCY2C
Application: Flow Cyt
Price: 10μg ¥690.00 ; 50μg ¥2280.00 ; 100 μg ¥4080.00 ; 500 μg ¥13280.00
Monoclonal Antibodies
SKU: DMC100508 Target: GUCY2C
Application: WB
Price: 10μg ¥690.00 ; 50μg ¥2280.00 ; 100 μg ¥4080.00 ; 500 μg ¥13280.00
Biosimilar reference antibodies
SKU: BME100180B Target: GUCY2C
Application: ELISA, Flow Cyt
Price: 50 μg ¥890.00 ; 100 μg ¥1699.00
Monoclonal Antibodies
Biotinylated Anti-GUCY2C antibody(DMC387); IgG1 Chimeric mAb
SKU: DMC100387B Target: GUCY2C
Application: Flow Cyt
Price: 10μg ¥1030.00 ; 50μg ¥3380.00 ; 100 μg ¥6080.00 ; 500 μg ¥19880.00
Biosimilar reference antibodies
SKU: BME100180P Target: GUCY2C
Application: Flow Cyt
Price: 100 test ¥1360.00