Name: Human GRM5 full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP100325

Tag	C-Flag Tag
Target	GRM5
Synonyms	GPRC1E, MGLUR5, PPP1R86, mGlu5
Description	Human GRM5 full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	P41594
Expression Host	HEK293
Protein Families	GPCR,Transmembrane,Druggable Genome,
Protein Pathways	GPCRDB Class C Metabotropic glutamate pheromone,
Molecular Weight	The human full length GRM5 protein has a MW of 132.5kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with pH lower than 6.5 in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Usage	Research use only
Conjugate	Unconjugated

Human GRM5 full length protein-synthetic nanodisc

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Human GRM5 full length protein-synthetic nanodisc

Product Data

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