| Tag | C-Flag Tag |
|---|---|
| Target | |
| Synonyms | GPRC5D |
| Description | Human GPRC5D full length protein-synthetic nanodisc |
| Delivery | In Stock |
| Uniprot ID | Q9NZD1 |
| Expression Host | HEK293 |
| Protein Families | GPCR |
| Protein Pathways | N/A |
| Molecular Weight | The human full length GPRC5D Protein has a MW of 38.6 kDa |
| Formulation & Reconstitution | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | The protein encoded by this gene is a member of the G protein-coupled receptor family. Recent studies demonstrate that GPRC5D is expressed on malignant bone marrow plasma cells, whereas normal tissue expression is limited to the hair follicle. It may represent a potential target for effector-cell–mediated therapy to treat plasma-cell disorders like MM. |
| Usage | Research use only |
| Conjugate | Unconjugated |
Human GPRC5D full length protein-synthetic nanodisc
Price: 10 μg ￥6300.00 ;50 μg ￥30000.00 ; 100 μg ￥55000.00
Product Data
图片
Figure1. Elisa plates were added with Flag Tag GPRC5D-Nanodisc (0.5μg/per well) on an anti-Flag monoclonal antibody pre-coated (0.5μg/per well) plate. Serial diluted anti-GPRC5D monoclonal antibody (DME100090) solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-GPRC5D monoclonal antibody binding with GPRC5D-Nanodisc is 32.86ng/ml.
Figure2. Human GPRC5D-Nanodisc, Flag Tag on SDS-PAGE
相关产品
Biosimilar reference antibodies
SKU: BME100072B Target: GPRC5D
Application: Flow Cyt
Price: 50 μg ￥890.00 ; 100 μg ￥1699.00
Full Length Transmembrane Proteins
SKU: FLP120011 Target: GPRC5D
Price: 10 μg ￥5670.00 ;50 μg ￥27000.00 ; 100 μg ￥49500.00
Biosimilar reference antibodies
SKU: BME100187B Target: GPRC5D
Application: Flow Cyt
Price: 50 μg ￥890.00 ; 100 μg ￥1699.00
Biosimilar reference antibodies
SKU: BME100193B Target: GPRC5D
Application: ELISA, Flow Cyt
Price: 50 μg ￥890.00 ; 100 μg ￥1699.00
Monoclonal Antibodies
SKU: DME100091B Target: GPRC5D
Application: Flow Cyt
Price: 10μg ￥1030.00 ; 50μg ￥3380.00 ; 100 μg ￥6080.00 ; 500 μg ￥19880.00