Name: Human GNRHR-Strep full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP120092

Tag	C-Flag&Strep Tag
Target	GNRHR
Synonyms	GNRHR1; GRHR; HH7; LHRHR; LRHR
Description	Human GNRHR-Strep full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	P30968
Expression Host	HEK293
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	GnRH signaling pathway, Neuroactive ligand-receptor interaction
Molecular Weight	The human full length GNRHR-Strep protein has a MW of 37.7 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	The receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms.
Usage	Research use only
Conjugate	Unconjugated

Human GNRHR-Strep full length protein-synthetic nanodisc

Product Data

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Human GNRHR-Strep full length protein-synthetic nanodisc

Product Data

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