Human GIPR-Strep full length protein-synthetic nanodisc

Price: 10 μg ￥5670.00 ;50 μg ￥27000.00 ; 100 μg ￥49500.00

SKU: FLP120130 Category: Full Length Transmembrane Proteins

Tag	C-Flag&Strep Tag
Target	GIPR
Synonyms	PGQTL2
Description	Human GIPR-Strep full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	P48546
Expression Host	HEK293
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	Neuroactive ligand-receptor interaction
Molecular Weight	The human full length GIPR-Strep protein has a MW of 53.2 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	A G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes.
Usage	Research use only
Conjugate	Unconjugated