Human GCGR-Strep full length protein-synthetic nanodisc

Name: Human GCGR-Strep full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP120085

Price: 10 μg ￥5670.00 ;50 μg ￥27000.00 ; 100 μg ￥49500.00

SKU: FLP120085 Category: Full Length Transmembrane Proteins

Datasheet

MSDS

Product Data

Tag	C-Flag&Strep Tag
Target	GCGR
Synonyms	GGR; GL-R; MVAH
Description	Human GCGR-Strep full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	P47871
Expression Host	HEK293
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	Neuroactive ligand-receptor interaction
Molecular Weight	The human full length GCGR-Strep protein has a MW of 54 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C(Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.
Usage	Research use only
Conjugate	Unconjugated

Human GCGR-Strep full length protein-synthetic nanodisc

Product Data

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