Name: Human FZD7 Protein, hFc Tag - 专注肿瘤免疫
SKU: PME101180
Price: 3699.00 CNY
Availability: InStock

Target	FZD7
Synonyms	FzE3
Description	Recombinant Human FZD7 Protein with N-terminal human Fc tag
Delivery	In Stock
Uniprot ID	O75084
Expression Host	HEK293
Tag	N-Human Fc Tag
Molecular Characterization	hFc(Glu99-Ala330) FZD7(Gln33-Arg254)
Molecular Weight	The protein has a predicted molecular mass of 50.5 kDa after removal of the signal peptide. The apparent molecular mass of hFc-FZD7 is approximately 55-70 kDa due to glycosylation.
Purity	The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution	Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008]
Usage	Research use only
Conjugate	Unconjugated

Human FZD7 Protein, hFc Tag

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Human FZD7 Protein, hFc Tag

Product Data

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