Name: Human F2RL3-Strep full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP120114

Tag	C-Flag&Strep Tag
Target	F2RL3
Synonyms	PAR4
Description	Human F2RL3-Strep full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	Q96RI0
Expression Host	HEK293
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	Neuroactive ligand-receptor interaction
Molecular Weight	The human full length F2RL3-Strep protein has a MW of 41.1 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	A member of the protease-activated receptor subfamily, part of the G-protein coupled receptor 1 family of proteins. The encoded receptor is proteolytically processed to reveal an extracellular N-terminal tethered ligand that binds to and activates the receptor. This receptor plays a role in blood coagulation, inflammation and response to pain. Hypomethylation at this gene may be associated with lung cancer in human patients.
Usage	Research use only
Conjugate	Unconjugated

Human F2RL3-Strep full length protein-synthetic nanodisc