Name: Human F2RL1-Strep full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP120036

Tag	C-Flag&Strep Tag
Target	F2RL1
Synonyms	GPR11; PAR2
Description	Human F2RL1-Strep full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	P55085
Expression Host	HEK293
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	Neuroactive ligand-receptor interaction
Molecular Weight	The human full length F2RL1-Strep protein has a MW of 44.1 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	A member of the G-protein coupled receptor 1 family of proteins. The encoded cell surface receptor is activated through proteolytic cleavage of its extracellular amino terminus, resulting in a new amino terminus that acts as a tethered ligand that binds to an extracellular loop domain. Activation of the receptor has been shown to stimulate vascular smooth muscle relaxation, dilate blood vessels, increase blood flow, and lower blood pressure. This protein is also important in the inflammatory response, as well as innate and adaptive immunity.
Usage	Research use only
Conjugate	Unconjugated

Human F2RL1-Strep full length protein-synthetic nanodisc