Name: Human CLTR1 full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP100224

Tag	C-Flag Tag
Target	CLTR1
Synonyms	CYSLT1, CYSLT1R, CYSLTR, HMTMF81
Description	Human CLTR1 full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	Q9Y271
Expression Host	HEK293
Protein Families	GPCR,Transmembrane,Druggable Genome,
Protein Pathways	GPCRDB Class A Rhodopsin-like,Cancer,Asthma,Autoimmune & Inflammatory Response,
Molecular Weight	The human full length CLTR1 protein has a MW of 38.5kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	This gene encodes a member of the G-protein coupled receptor 1 family. The encoded protein is a receptor for cysteinyl leukotrienes, and is involved in mediating bronchoconstriction via activation of a phosphatidylinositol-calcium second messenger system. Activation of the encoded receptor results in contraction and proliferation of bronchial smooth muscle cells, eosinophil migration, and damage to the mucus layer in the lung. Upregulation of this gene is associated with asthma and dysregulation may also be implicated in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Usage	Research use only
Conjugate	Unconjugated

Human CLTR1 full length protein-synthetic nanodisc

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Human CLTR1 full length protein-synthetic nanodisc

Product Data

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