Name: Human CLDN9-Strep full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP120081

Tag	C-Flag&Strep Tag
Target	CLDN9
Synonyms	DFNB116
Description	Human CLDN9-Strep full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	O95484
Expression Host	HEK293
Protein Families	Transmembrane
Protein Pathways	Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction
Molecular Weight	The human full length CLDN9-Strep protein has a MW of 22.8 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C(Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	This protein is a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein is one of the entry cofactors for hepatitis C virus. Mouse studies revealed that this gene is required for the preservation of sensory cells in the hearing organ and the gene deficiency is associated with deafness.
Usage	Research use only
Conjugate	Unconjugated

Human CLDN9-Strep full length protein-synthetic nanodisc

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Human CLDN9-Strep full length protein-synthetic nanodisc

Product Data

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