Name: Human CLDN2-Strep full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP120082

Tag	C-Flag&Strep Tag
Target	CLDN2
Synonyms	OAZON
Description	Human CLDN2-Strep full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	P57739
Expression Host	HEK293
Protein Families	Transmembrane
Protein Pathways	Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction
Molecular Weight	The human full length CLDN2-Strep protein has a MW of 24.5 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with pH lower than 6.5 in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C(Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	This protein belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.
Usage	Research use only
Conjugate	Unconjugated

Human CLDN2-Strep full length protein-synthetic nanodisc