Human CD74 (73-296) Protein, hFc Tag

Name: Human CD74 (73-296) Protein, hFc Tag - 专注肿瘤免疫
SKU: PME100642
Price: 3499.00 USD
Availability: InStock

Price: 10μg ￥636.00 ; 50μg ￥2333.00 ; 100 μg ￥3499.00

SKU: PME100642 Category: ECD Proteins

Datasheet

MSDS

Product Data

Target	CD74
Synonyms	DHLAG;HLADG;Ia-GAMMA;II;p33
Description	Recombinant Human CD74(73-296) Protein with N-terminal human Fc tag
Delivery	In Stock
Uniprot ID	P04233
Expression Host	HEK293
Tag	N-Human Fc Tag
Molecular Characterization	hFc(Glu99-Ala330) CD74(Gln73-Met296)
Molecular Weight	The protein has a predicted molecular mass of 51.5 kDa after removal of the signal peptide.The apparent molecular mass of hFc-CD74(73-296) is approximately 55-70 kDa due to glycosylation.
Purity	The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution	Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
Usage	Research use only

图片

Figure 1. Human CD74(73-296) Protein, hFc Tag on SDS-PAGE under reducing condition.
PME100642-CD74-Fig.2-Elisa-1.jpg
Figure 2. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human CD74 (73-296) Protein, hFc Tag (PME100642) can bind Anti-CD74(milatuzumab biosimilar) mAb (BME100170) in a linear range of 0.64–16 ng/mL.

Human CD74 (73-296) Protein, hFc Tag

Product Data

图片

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