Target | |
---|---|
Synonyms | BN-1; C-C CKR-6; CC-CKR-6; CCR-6; CD196; CKR-L3; CKRL3; CMKBR6; DCR2; DRY6; GPR29; GPRCY4; STRL22 |
Description | Human CCR6 full length protein-MNP |
Delivery | In Stock |
Uniprot ID | P51684 |
Expression Host | HEK293 |
Protein Families | Druggable Genome, GPCR, Transmembrane |
Protein Pathways | Chemokine signaling pathway, Cytokine-cytokine receptor interaction |
Molecular Weight | The human full length CCR6 protein has a MW of 42.5 kDa |
Formulation & Reconstitution | Lyophilized from PBS. Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | The protein is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. |
Usage | Research use only |
Conjugate | Unconjugated |
Human CCR6 full length protein-MNP
Price: 50 μg ¥8000.00 ; 100 μg ¥10800.00
Product Data
图片
Figure 1. Elisa plates were pre-coated with 0.5μg/per well purified human CCR6 full length membrane nanoparticles. Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with CCR6 full length membrane nanoparticles is 13.24ng/ml.
相关产品
Full Length Transmembrane Proteins
SKU: FLP120059 Target: CCR6
Price: 10 μg ¥5670.00 ;50 μg ¥27000.00 ; 100 μg ¥49500.00
Full Length Transmembrane Proteins
SKU: FLP100059 Target: CCR6
Price: 10 μg ¥6300.00 ;50 μg ¥30000.00 ; 100 μg ¥55000.00
ECD Proteins
SKU: PME-M100106 Target: CCR6
Price: 10μg ¥600.00 ; 50μg ¥2199.00 ; 100μg ¥3299.00
ECD Proteins
SKU: PME101105 Target: CCR6
Price: 10μg ¥636.00 ; 50μg ¥2333.00 ; 100 μg ¥3499.00
ECD Proteins
SKU: PME100660 Target: CCR6
Price: 10μg ¥673.00 ; 50μg ¥2466.00 ; 100 μg ¥3699.00