Target | |
---|---|
Synonyms | C-C Motif Chemokine 26;CC Chemokine IMAC;Eotaxin-3;Macrophage Inflammatory Protein 4-Alpha;MIP-4-Alpha;Small-Inducible Cytokine A26;Thymic Stroma Chemokine-1;TSC-1;CCL26;SCYA26 |
Description | Recombinant Human C-C Motif Chemokine 26 is produced by our E.coli expression system and the target gene encoding Ser27-Leu94 is expressed. |
Delivery | In Stock |
Uniprot ID | Q9Y258 |
Expression Host | E.coli |
Tag | |
Molecular Characterization | Not available |
Molecular Weight | Predicted MW is 8.21 Kda. Protein runs at 13KDa under reducing conditions. |
Purity | Greater than 95% as determined by reducing SDS-PAGE. |
Formulation & Reconstitution | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
Storage & Shipping | Lyophilized protein should be stored at -20°C or lower, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at -20°C or lower for 3 months. The product is shipped at ambient temperature. Upon receipt, store it immediately at the proper temperature. |
Background | Chemokine (C C Motif) Ligand 26 (CCL26) is a novel small cytokine belonging to the CC chemokine family, which involved in immunoregulatory and inflammatory processes. CCL26 is expressed constitutively in thymus, but only transiently in phytohemagglutinin-stimulated peripheral blood mononuclear cells. It specifically binds and induces chemotaxis in T cells and elicits its effects by interacting with the chemokine receptor CCR4. Eotaxin-3/CCL26, along with Eotaxin-1 and Eotaxin-2, selectively activates the CC chemokine receptor 3 (CCR3). The Eotaxin-3-CCR3 interaction may play an important role in allergic diseases such as atopic dermatitis and bronchial asthma. The full-length cDNA for Eotaxin-3 encodes a protein of 94 amino acids with a putative signal peptide of either 23 or 26 amino acid residues. Both the 71 and 68 amino acid residue variants of recombinant Eotaxin-3 demonstrate equal potency in inducing chemotaxis of a human CCR3-transfected cell line. Unlike most other CC chemokines, Eotaxin-3 maps to human chromosome 7q11.2, within 40 kilobases of the Eotaxin-2 loci. Eotaxin-3 and Eotaxin-2 are unique in that they are the only chemokines identified to date that map to chromosome 7. |
Usage | Research use only |
Human CCL26 (68AA) Protein
Price: 10 μg ¥1024.00 ; 50 μg ¥3080.00
Product Data
图片
Figure 1. Greater than 95% as determined by reducing SDS-PAGE.
相关产品
ECD Proteins
SKU: PME100004 Target: CD38
Price: 10μg ¥727.00 ; 50μg ¥2666.00 ; 100 μg ¥3999.00
ECD Proteins
SKU: PME100012 Target: B7-H3
Price: 10μg ¥782.00 ; 50μg ¥2866.00 ; 100 μg ¥4299.00
ECD Proteins
SKU: PME100003 Target: CD123
Price: 10μg ¥727.00 ; 50μg ¥2666.00 ; 100 μg ¥3999.00
ECD Proteins
SKU: PME100009 Target: SIRPa
Price: 10μg ¥782.00 ; 50μg ¥2866.00 ; 100 μg ¥4299.00
ECD Proteins
SKU: PME100010 Target: 2B4
Price: 10μg ¥727.00 ; 50μg ¥2666.00 ; 100 μg ¥3999.00
ECD Proteins
SKU: PME100011 Target: 4-1BB
Price: 10μg ¥909.00 ; 50μg ¥3333.00 ; 100 μg ¥4999.00
ECD Proteins
SKU: PME100014 Target: CD28
Price: 10μg ¥909.00 ; 50μg ¥3333.00 ; 100 μg ¥4999.00
ECD Proteins
SKU: PME100025 Target: PD-1
Price: 10μg ¥909.00 ; 50μg ¥3333.00 ; 100 μg ¥4999.00
ECD Proteins
SKU: PME100021 Target: OX40 Ligand
Price: 10μg ¥909.00 ; 50μg ¥3333.00 ; 100 μg ¥4999.00
ECD Proteins
SKU: PME100005 Target: CD22
Price: 10μg ¥782.00 ; 50μg ¥2866.00 ; 100 μg ¥4299.00
ECD Proteins
SKU: PME100671 Target: RSPO3
Price: 10μg ¥673.00 ; 50μg ¥2466.00 ; 100 μg ¥3699.00
ECD Proteins
SKU: PME100667 Target: GFAP
Price: 10μg ¥673.00 ; 50μg ¥2466.00 ; 100 μg ¥3699.00