Human GPR77 full length protein-synthetic nanodisc

Name: Human GPR77 full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP100069
Price: 55000.00 CNY
Availability: InStock

Price: 10 μg ￥6300.00 ;50 μg ￥30000.00 ; 100 μg ￥55000.00

SKU: FLP100069 Category: Full Length Transmembrane Proteins Tag: synthetic nanodisc

Datasheet

MSDS

Product Data

Tag	C-Flag Tag
Target	C5AR2
Synonyms	C5L2; GPF77; GPR77
Description	Human GPR77 full length protein-synthetic nanodisc
Delivery	3-4 weeks
Uniprot ID	Q9P296
Expression Host	HEK293
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	N/A
Molecular Weight	The human full length C5AR2 protein has a MW of 36.1 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
Usage	Research use only
Conjugate	Unconjugated

图片

elisa-FLP100069 GPR77 Fig.1 Elisa 1
Figure1. Elisa plates were pre-coated with Flag Tag GPR77-Nanodisc (0.2μg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with GPR77-Nanodisc is 3.415ng/ml.
page-FLP100069 GPR77 Fig.2 SDS PAGE 1
Figure2. Human GPR77-Nanodisc, Flag Tag on SDS-PAGE

Human GPR77 full length protein-synthetic nanodisc

Product Data

图片

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