Human BCMA Protein, mFc Tag

Name: Human BCMA Protein, mFc Tag - 专注肿瘤免疫
SKU: PME100035
Price: 4999.00 CNY
Availability: InStock

Price: 10μg ￥909.00 ; 50μg ￥3333.00 ; 100 μg ￥4999.00

SKU: PME100035 Category: ECD Proteins

Datasheet

MSDS

Product Data

Target	BCMA
Synonyms	TNFRSF17;CD269;BCM;BCMA
Description	Recombinant human BCMA protein with C-terminal mouse Fc tag
Delivery	In Stock
Uniprot ID	Q02223
Expression Host	HEK293
Tag	C-Mouse Fc Tag
Molecular Characterization	BCMA(Met1-Ala54) mFc(Pro99-Lys330)
Molecular Weight	The protein has a predicted molecular mass of 32.1 kDa after removal of the signal peptide.
Purity	The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution	Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	B-cell maturation protein (BCMA or BCM), is also known as Tumor necrosis factor receptor superfamily member 17 (TNFRSF17), which is encoded by the TNFRSF17 gene. TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). This receptor is expressed in immune organs and mature B cell lines. BCMA promotes B-cell survival and plays a role in the regulation of humoral immunity. BCMA can activate NF-kappa-B and JNK.
Usage	Research use only
Conjugate	Unconjugated

图片

Figure 1. Human BCMA, mFc Tag on SDS-PAGE under reducing condition.
PME100035-BCMA-mFc-ELISA-Figure 2.png
Figure 2. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human BAFF, hFc tagged protein PME100043 can bind Human BCMA, mFc tagged protein (PME100035) in a linear range of 0.03-15.625 ng/ml.

Figure 3. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human BCMA, mFc tagged protein (PME100035) can bind Anti-BCMA Neutralizing antibody BME100028 in a linear range of 0.64-80.0 ng/ml.

Figure 4. Flow cytometry analysis with 1μg/ml Human BCMA Protein, mFc tag (PME100035) on Expi293 cells transfected with human BAFF (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

Human BCMA Protein, mFc Tag

Product Data

图片

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