Human BCMA Protein, hFc-His Tag

Name: Human BCMA Protein, hFc-His Tag - 专注肿瘤免疫
SKU: PME100001
Price: 4299.00 CNY
Availability: InStock

Price: 10μg ￥782.00 ; 50μg ￥2866.00 ; 100 μg ￥4299.00

SKU: PME100001 Category: ECD Proteins

Datasheet

MSDS

Product Data

Target	BCMA
Synonyms	TNFRSF17;CD269;BCM;BCMA
Description	Recombinant human BCMA protein with C-terminal human Fc and 6×His tag
Delivery	In Stock
Uniprot ID	Q02223
Expression Host	HEK293
Tag	C-Human Fc and 6×His Tag
Molecular Characterization	BCMA(Leu2-Ala54) hFc(Glu99-Ala330) 6×His tag
Molecular Weight	The protein has a predicted molecular mass of 32.7 kDa after removal of the signal peptide. The apparent molecular mass of BCMA-hFc-His is approximately 40 kDa due to glycosylation.
Purity	The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution	Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	B-cell maturation protein (BCMA or BCM), is also known as Tumor necrosis factor receptor superfamily member 17 (TNFRSF17), which is encoded by the TNFRSF17 gene. TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). This receptor is expressed in immune organs and mature B cell lines. BCMA promotes B-cell survival and plays a role in the regulation of humoral immunity. BCMA can activate NF-kappa-B and JNK.
Usage	Research use only
Conjugate	Unconjugated

图片

Figure 1. Human BCMA, hFc-His Tag on SDS-PAGE under reducing condition.

Figure 2. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human BCMA, hFc-His tagged protein can bind Anti-BCMA (Neutralizing antibody clone huC11D5.3) BME100016 in a linear range of 3.71-22.29 ng/ml.

Human BCMA Protein, hFc-His Tag

Product Data

图片

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