Name: Human BACD1 full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP100718

Tag	C-Flag Tag
Target	BACD1
Synonyms	BACURD1, FKSG86, PDIP1, POLDIP1, hBACURD1
Description	Human BACD1 full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	Q8WZ19
Expression Host	HEK293
Protein Families	Ion Channels: Other
Protein Pathways	N/A
Molecular Weight	The human full length BACD1 protein has a MW of 36.4kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for synaptic transmission (PubMed:19782033). The BCR(KCTD13) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome (PubMed:19782033) Degradation of RHOA regulates the actin cytoskeleton and promotes synaptic transmission (By similarity).[UniProtKB/Swiss-Prot Function]
Usage	Research use only
Conjugate	Unconjugated

Human BACD1 full length protein-synthetic nanodisc