Name: Human APLNR-Strep full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP120132

Tag	C-Flag&Strep Tag
Target	APLNR
Synonyms	AGTRL1; APJ; APJR; HG11
Description	Human APLNR-Strep full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	P35414
Expression Host	HEK293
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	Neuroactive ligand-receptor interaction
Molecular Weight	The human full length APLNR-Strep protein has a MW of 42.7 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	A member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified.
Usage	Research use only
Conjugate	Unconjugated

Human APLNR-Strep full length protein-synthetic nanodisc