Name: Human AGRL1 full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP100207

Tag	C-Flag Tag
Target	AGRL1
Synonyms	CIRL1, CL1, LEC2, LPHN1
Description	Human AGRL1 full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	O94910
Expression Host	HEK293
Protein Families	Transmembrane,Druggable Genome,
Protein Pathways	GPCRDB Class B Secretin-like,
Molecular Weight	The human full length AGRL1 protein has a MW of 162.7kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with pH lower than 6.5 in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Oct 2008]
Usage	Research use only
Conjugate	Unconjugated

Human AGRL1 full length protein-synthetic nanodisc

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Human AGRL1 full length protein-synthetic nanodisc

Product Data

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