Target | |
---|---|
Synonyms | A3AR |
Description | Recombinant human ADORA3 protein with C-terminal human Fc tag |
Delivery | Under development |
Uniprot ID | P0DMS8 |
Expression Host | HEK293 |
Tag | C-Human Fc Tag |
Molecular Characterization | ADORA3(Trp149-Met177) hFc(Glu99-Ala330) |
Molecular Weight | The protein has a predicted molecular mass of 38.72 kDa after removal of the signal peptide. |
Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Alternative splicing results in multiple transcript variants. This gene shares its 5' terminal exon with some transcripts from overlapping GeneID:57413, which encodes an immunoglobulin domain-containing protein. [provided by RefSeq, Nov 2014] |
Usage | Research use only |
Human ADORA3 Protein, hFc Tag
Price: 10μg ¥673.00 ; 50μg ¥2466.00 ; 100 μg ¥3699.00
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