| Target | |
|---|---|
| Synonyms | ACVRLK1;ALK-1;ALK1;HHT;HHT2;ORW2;SKR3;TSR-I |
| Description | Recombinant Human ACVRL1 Protein with C-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | P37023 |
| Expression Host | HEK293 |
| Tag | C-Human Fc Tag |
| Molecular Characterization | ACVRL1(Asp22-Gln118) hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 36.8 kDa after removal of the signal peptide. The apparent molecular mass of ACVRL1-hFc is approximately 35-70 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. [provided by RefSeq, Jul 2008] |
| Usage | Research use only |
| Conjugate | Unconjugated |
Human ACVRL1 Protein, hFc Tag
Price: 10μg ￥600.00 ; 50μg ￥2199.00 ; 100μg ￥3299.00
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Figure 1.Human ACVRL1 Protein, hFc Tag on SDS-PAGE under reducing condition.
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