Name: Human ACHD full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP100797

Tag	C-Flag Tag
Target	ACHD
Synonyms	ACHRD, CMS2A, CMS3A, CMS3B, CMS3C, FCCMS, SCCMS
Description	Human ACHD full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	Q07001
Expression Host	HEK293
Protein Families	Ion Channels: Cys-loop Receptors
Protein Pathways	N/A
Molecular Weight	The human full length ACHD protein has a MW of 58.9kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in this gene are a cause of multiple pterygium syndrome lethal type (MUPSL), congenital myasthenic syndrome slow-channel type (SCCMS), and congenital myasthenic syndrome fast-channel type (FCCMS). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2015]
Usage	Research use only
Conjugate	Unconjugated

Human ACHD full length protein-synthetic nanodisc

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Human ACHD full length protein-synthetic nanodisc

Product Data

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