Name: Human ACH10 full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP100792

Tag	C-Flag Tag
Target	ACH10
Synonyms	N/A
Description	Human ACH10 full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	Q9GZZ6
Expression Host	HEK293
Protein Families	Ion Channels: Cys-loop Receptors
Protein Pathways	N/A
Molecular Weight	The human full length ACH10 protein has a MW of 49.7kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.[UniProtKB/Swiss-Prot Function]
Usage	Research use only
Conjugate	Unconjugated

Human ACH10 full length protein-synthetic nanodisc

Product Data

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Human ACH10 full length protein-synthetic nanodisc

Product Data

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