Name: Human 5HT3A full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP100779

Tag	C-Flag Tag
Target	5HT3A
Synonyms	5-HT-3, 5-HT3A, 5-HT3R, 5HT3R, HTR3
Description	Human 5HT3A full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	P46098
Expression Host	HEK293
Protein Families	Ion Channels: Cys-loop Receptors
Protein Pathways	N/A
Molecular Weight	The human full length 5HT3A protein has a MW of 55.3kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Usage	Research use only
Conjugate	Unconjugated

Human 5HT3A full length protein-synthetic nanodisc

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Human 5HT3A full length protein-synthetic nanodisc

Product Data

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