| Tag | C-Flag Tag |
|---|---|
| Target | |
| Synonyms | 5-HT2A, HTR2 |
| Description | Human 5HT2A full length protein-synthetic nanodisc |
| Delivery | 6~8weeks |
| Uniprot ID | P28223 |
| Expression Host | HEK293 |
| Protein Families | GPCR,Transmembrane,Druggable Genome, |
| Protein Pathways | GPCRDB Class A Rhodopsin-like,GPCRDB Other,Monoamine GPCRs,Metabolic and Obesity, |
| Molecular Weight | The human full length 5HT2A protein has a MW of 52.6kDa |
| Formulation & Reconstitution | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] |
| Usage | Research use only |
| Conjugate | Unconjugated |
Human 5HT2A full length protein-synthetic nanodisc
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Full Length Transmembrane Proteins
SKU: FLP120166 Target: 5HT2A
Price: 10 μg ￥5670.00 ;50 μg ￥27000.00 ; 100 μg ￥49500.00