Clone ID | 1000000 |
---|---|
Target | |
Synonyms | N.A. |
Host Species | Rabbit |
Description | Biotinylated Anti-Dxd antibody(1E6); Rabbit mAb |
Delivery | 2-3 weeks |
Uniprot ID | N.A. |
IgG type | Rabbit IgG |
Clonality | Monoclonal |
Reactivity | N.A. |
Applications | ELISA |
Recommended Dilutions | ELISA 1:5000-10000 |
Purification | Purified from cell culture supernatant by affinity chromatography |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | Dxd is a potent anti-cancer drug, acting as an alkaloid camptothecin analog and a DNA topoisomerase I inhibitor. It forms a stable complex with topoisomerase I and DNA, impeding DNA replication and inducing cancer cell death. Dxd is utilized as a payload in specific antibody-drug conjugates (ADCs), with examples such as trastuzumab deruxtecan targeting HER2 and patritumab deruxtecan targeting HER3. |
Usage | Research use only |
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Biotinylated Anti-Dxd antibody(1E6); Rabbit mAb
Price: 10μg ¥1030.00 ; 50μg ¥3380.00 ; 100 μg ¥6080.00 ; 500 μg ¥19880.00
Product Data
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