| Common Name | IMMU-132, hRS7-SN-38, hRS7-SN-38-ADC, hRS7-[CL-SN-38], hrS7-SN-38 |
|---|---|
| Synonyms | TACSTD2;GA733-1;M1S1;TROP2 |
| Applications | ELISA; Flow Cyt |
| Recommended Dilutions | ELISA 1:5000-10000; Flow Cyt 1:100 |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Host Species | Humanized |
| IgG type | IgG1 |
| Reactivity | Human |
| Target | |
| Uniprot ID | P09758 |
| Description | Anti-Trop2 (sacituzumab biosimilar) mAb |
| Delivery | In Stock |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | Research grade biosimilar. Not for use in therapeutic or diagnostic procedures for humans or animals. |
| Usage | Research use only；All DIMA recombinant antibodies are genuinely generated by DIMA Biotech. They are all under patent application. Any protein sequencing or reverse engineering attempt is prohibited. We are actively scrutinizing all patent application to ensure no IP infringement. |
| Conjugate | Unconjugated |
Anti-Trop2 (sacituzumab biosimilar) mAb
Price: 50 μg ￥800.00 ; 100 μg ￥1500.00
Product Data
图片
Figure 1. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human Trop2, mFc-His tagged protein PME100501 can bind Anti-Trop2 Neutralizing antibody in a linear range of 0.13-16.0 ng/ml.
Figure 2. Flow cytometry analysis of antigen binding of anti-human Trop2 mAb(BME100023).
(A) BME100023 does not bind to 293T cells that do not express Trop2.
(B) A clear peak shift of BME100023 was seen compared to the control when incubated with Trop2-expressing A431 cells, indicating strong binding of BME100023 to Trop2. Antibodies were incubated at 2 μg/mL.
Figure 3. HEK293 cell line transfected with irrelevant protein (B) and human Trop2 protein (A) were surface stained with anti-Trop2 neutralizing antibody 1μg/ml (sacituzumab) followed by Alexa 488-conjugated anti-human IgG secondary antibody.
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