Anti-TNFRSF1B antibody(8C4); IgG1 Chimeric mAb

Name: Anti-TNFRSF1B antibody(8C4); IgG1 Chimeric mAb - 专注肿瘤免疫
SKU: DMC101037

Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

SKU: DMC101037 Category: Monoclonal Antibodies

Datasheet

MSDS

Product Data

Clone ID	8C4
Target	TNFRSF1B
Synonyms	CD120b;p75;p75TNFR;TBPII;TNF-R-II;TNF-R75;TNFBR;TNFR1B;TNFR2;TNFR80
Host Species	Rabbit
Description	Anti-TNFRSF1B antibody(8C4); IgG1 Chimeric mAb
Delivery	In Stock
Uniprot ID	P20333
IgG type	Rabbit/Human Fc chimeric IgG1
Clonality	Monoclonal
Reactivity	Human
Applications	Flow Cyt
Recommended Dilutions	Flow Cyt 1/100
Purification	Purified from cell culture supernatant by affinity chromatography
Formulation & Reconstitution	Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq, Jul 2008]
Usage	Research use only
Conjugate	Unconjugated
DIMA Disclaimer	All DIMA recombinant antibodies are genuinely generated by DIMA Biotech. They are all under patent application. Any protein sequencing or reverse engineering attempt is prohibited. We are actively scrutinizing all patent application to ensure no IP infringement.

图片

antibody-DMC101037 TNFRSF1B Fig.1 FC 1
Figure 1. Flow cytometry analysis with Anti-TNFRSF1B (8C4) mAb on Expi293 cells transfected with human TNFRSF1B (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

Anti-TNFRSF1B antibody(8C4); IgG1 Chimeric mAb

Product Data

图片

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