Clone ID | 68H10 |
---|---|
Target | |
Synonyms | PSGL-1,PSGL1,CD162,Selectin P ligand |
Host Species | Rabbit |
Description | Anti-SELPLG antibody(68H10), IgG1 Chimeric mAb |
Delivery | In Stock |
Uniprot ID | A0A7N9CVJ8 |
IgG type | Rabbit/Human Fc chimeric IgG1 |
Clonality | Monoclonal |
Reactivity | Human |
Applications | IHC |
Recommended Dilutions | IHC 1:100 |
Purification | Purified from cell culture supernatant by affinity chromatography |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants. |
Usage | Research use only |
Anti-SELPLG antibody(68H10), IgG1 Chimeric mAb
Price: 10μg ¥690.00 ; 50μg ¥2280.00 ; 100 μg ¥4080.00 ; 500 μg ¥13280.00
Product Data
图片
Figure 1. A. DMC100741 at 10µg/ml staining SELPLG in MM.1S xenografts in nude mice by IHC (SKU# DMC100741);B. DMC100741 at 10µg/ml staining SELPLG in human tonsil tissue by IHC (SKU# DMC100741)
相关产品
ECD Proteins
SKU: PME-C100016 Target: SELPLG
Price: 10μg ¥668.00; 50μg ¥2333.00 ; 100 μg ¥3499.00
ECD Proteins
SKU: PME100471 Target: SELPLG
Price: 10μg ¥727.00 ; 50μg ¥2666.00 ; 100 μg ¥3999.00
Monoclonal Antibodies
SKU: DMC100283B Target: SELPLG
Application: Flow Cyt
Price: 10μg ¥1030.00 ; 50μg ¥3380.00 ; 100 μg ¥6080.00 ; 500 μg ¥19880.00
DiSliceX
SKU: SLI100001 Target: BCMA, BTN3A1, CD138, CD147, CD30, CD33, CD38, CD47, CD63, CD99, CS1, GITR, GPC1, GPRC5D, ICAM-1, MUC1, PDL-1, SELPLG, TFRC, TIM3
Application: IHC
Price: 2 slides ¥899.00
DiSliceX
SKU: SLI100002 Target: BTN3A2, CCR1, CD138, CD147, CD164, CD38, CXCR3, GPRC5D, KI67, LGALS1, SELPLG
Application: IHC
Price: 2 slides ¥899.00