Anti-IFNAR1(anifrolumab biosimilar) mAb

Name: Anti-IFNAR1(anifrolumab biosimilar) mAb - 专注肿瘤免疫
SKU: BME100117
Price: 160.00 CNY
Availability: InStock

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

SKU: BME100117 Category: Biosimilar reference antibodies

Datasheet

MSDS

Product Data

Common Name	MDX-1333, MEDI-546, anifrolumab-fnia
Synonyms	IFN-R-1;CRF2-1;IFNAR
Applications	ELISA; Flow Cyt
Recommended Dilutions	ELISA 1:5000-10000; Flow Cyt 1:100
Formulation & Reconstitution	Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Host Species	Homo sapiens
IgG type	IgG1
Reactivity	Human
Target	IFNAR1
Uniprot ID	P17181
Description	Anti-IFNAR1(anifrolumab biosimilar) mAb
Delivery	In Stock
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	Research grade biosimilar. Not for use in therapeutic or diagnostic procedures for humans or animals.
Usage	Research use only
Conjugate	Unconjugated

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Elisa-BME100117 BM327Anti IFNAR1 ELISA Fig1

Figure 1. ELISA plate pre-coated by 1 μg/mL (100 μL/well) Human IFNAR1 Protein, His Tag (PME100958) can bind Anti-IFNAR1 Neutralizing antibody (BME100117) in a linear range of 0.61–39.06 ng/mL.

Elisa-BME100117 BM327 Anti IFNAR1 ELISA Fig2

Figure 2. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human IFNAR1 Protein, hFc Tag (PME100773) can bind Anti-IFNAR1 Neutralizing antibody (BME100117) in a linear range of 0.73–187.50 ng/mL. In order to specifically detect BME100117, mouse anti-human Fab-specific antibody was used as detection antibody.

Elisa-BME100117 BM327 Anti IFNAR1 ELISA Fig3

Figure 3. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human IFNAR1 Protein, mFc Tag (PME100737) can bind Anti-IFNAR1 Neutralizing antibody (BME100117) in a linear range of 1.22–312.50 ng/mL.

FC-BME100117 BM327 Anti IFNAR1 FACS Fig3

Figure 4. Flow cytometry analysis with 1 μg/mL Anti-IFNAR1 (anifrolumab biosimilar) mAb (BME100117) on Expi293 cells transfected with Human IFNAR1 protein (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

Anti-IFNAR1(anifrolumab biosimilar) mAb

Product Data

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