Anti-GPA33 antibody(DMC497); IgG1 Chimeric mAb

Name: Anti-GPA33 antibody(DMC497); IgG1 Chimeric mAb - 专注肿瘤免疫
SKU: DMC100497

Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

SKU: DMC100497 Category: Monoclonal Antibodies

Datasheet

MSDS

Product Data

Clone ID	DMC497
Target	GPA33
Synonyms	A33
Host Species	Rabbit
Description	Anti-GPA33 antibody(DMC497); IgG1 Chimeric mAb
Delivery	In Stock
Uniprot ID	Q99795
IgG type	Rabbit/Human Fc chimeric IgG1
Clonality	Monoclonal
Reactivity	Human
Applications	Flow Cyt
Recommended Dilutions	Flow Cyt 1:100
Purification	Purified from cell culture supernatant by affinity chromatography
Formulation & Reconstitution	Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region; a single transmembrane domain; and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily. [provided by RefSeq; Jul 2008]
Usage	Research use only；All DIMA recombinant antibodies are genuinely generated by DIMA Biotech. They are all under patent application. Any protein sequencing or reverse engineering attempt is prohibited. We are actively scrutinizing all patent application to ensure no IP infringement.
Conjugate	Unconjugated

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DMC100497-GPA33-Fig.1-FC-1.jpg
Figure 1. Flow cytometry analysis with Anti-GPA33 (DMC497) on Expi293 cells transfected with human GPA33 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

Figure 2. Flow cytometry analysis of antigen binding of anti-human GPA33 mAb(DMC100497).
(A) DMC100497 does not bind to 293T cells that do not express GPA33.
(B) A clear peak shift of DMC100497 was seen compared to the control when incubated with GPA33-expressing HT55 cells, indicating strong binding of DMC100497 to GPA33. Antibodies were incubated at 5 μg/mL.

Anti-GPA33 antibody(DMC497); IgG1 Chimeric mAb

Product Data

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