Anti-DDR1 antibody(DMC480); IgG1 Chimeric mAb

Name: Anti-DDR1 antibody(DMC480); IgG1 Chimeric mAb - 专注肿瘤免疫
SKU: DMC100480

Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

SKU: DMC100480 Category: Monoclonal Antibodies

Datasheet

MSDS

Product Data

Clone ID	DMC480
Target	DDR1
Synonyms	CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE; MCK-10; HGK2; CD167a
Host Species	Rabbit
Description	Anti-DDR1 antibody(DMC480); IgG1 Chimeric mAb
Delivery	In Stock
Uniprot ID	Q08345
IgG type	Rabbit/Human Fc chimeric IgG1
Clonality	Monoclonal
Reactivity	Human
Applications	Flow Cyt
Recommended Dilutions	Flow Cyt 1:100
Purification	Purified from cell culture supernatant by affinity chromatography
Formulation & Reconstitution	Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth; differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain; and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells; particularly in the kidney; lung; gastrointestinal tract; and brain. In addition; it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq; Feb 2011]
Usage	Research use only
Conjugate	Unconjugated

图片

DMC100480-DDR1-Fig.1-FC-1.jpg
Figure 1. Flow cytometry analysis with Anti-DDR1 (DMC480) on Expi293 cells transfected with human DDR1 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

Figure 2. Flow cytometry analysis of antigen binding of anti-human DDR1 mAb(DMC100480).
(A) DMC100480 does not bind to jurkat cells that do not express DDR1.
(B) A clear peak shift of DMC100480 was seen compared to the control when incubated with DDR1-expressing SNU-5 cells, indicating strong binding of DMC100480 to DDR1. Antibodies were incubated at 5 μg/mL.

Figure 3. Flow cytometry analysis of antigen binding of anti-human DDR1 mAb(DMC100480).
(A) DMC100480 does not bind to jurkat cells that do not express DDR1.
(B) A clear peak shift of DMC100480 was seen compared to the control when incubated with DDR1-expressing MCF-7 cells, indicating strong binding of DMC100480 to DDR1. Antibodies were incubated at 5 μg/mL.

Anti-DDR1 antibody(DMC480); IgG1 Chimeric mAb

Product Data

图片

相关产品

Login